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Revisiting nanoparticle technology for bloodbrain barrier transport: unfolding at the endothelial gate improves the fate of transferrin receptor-targeted liposomes

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Finally, one very recent study in the USA has demonstrated that in some individuals with neurological symptoms, the presence in the blood of antibodies against this receptor may interfere with the proper uptake of B12 into the brain

doi: 10.1016/j.molimm.2008.08.266 52 ZhuHBlumRHBjordahlRGaidarovaSRogersPLeeTTet al

Rita Cardoso B, Silva Bandeira V, Jacob-Filho W, Franciscato Cozzolino SM

It is classified as a nootropic peptide and is widely used to support cognitive function, mental performance, and neuroprotection