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CL Answer What is hesperidin, what is it used for and is it safe
In three studies, several patients did not complete the study and had a high risk of bias in the incomplete outcome data domain (Reference Oner and Muderris11,Reference Kose and Naziroglu26,Reference Fulghesu, Ciampelli and Muzj29)
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Intracrine androgen synthesis may have led to restored AR signaling, leading to a rise in PSA levels and recurrent tumor growth, a relapsed state commonly referred to as castration-resistant prostatic cancer (CRPC) 8
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