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Starting at just 10-25% of the approved starting doses for diabetes and obesity, followed by gradual dose escalation as tolerability is demonstrated, appears to be the key to success in MCAS patients
And the reason for that is several fold
A market can show strong starts while long-term continuation remains fragile
Sequence WeightWatchers clinical arm connecting patients with GLP-1 prescribers
Appetite control
Physical activity after injection can accelerate absorption
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