Cytoplasmic Fe 2+ further activates the expression of iron-containing proteases on the mitochondrial membrane, and then transports cytoplasmic Fe 2+ into mitochondria, producing mitochondrial ROS and ferroptosis
Xing RR, Liu K, Jiao TF, Zhang N, Ma K, Zhang RY, Zou QL, Ma GH, Yan XH
CNS GIPR KO mice resist development of diet-induced obesity To generate CNS-specific GIPR KO mice, Gipr fl/fl mice 17 were crossed to synapsin-Cre mice (Jackson Laboratories) to obtain Gipr fl/fl control mice and Gipr Syn/ mice (breeding schematic in Fig
Med Pharm
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