Signalling activates PLC- DAG + IP3 intracellular Ca + PKC (via Gq) plus Gs-cAMP-PKA, with a balanced profile neither Gs- nor -arrestin-biased in recent cryo-EM and BRET studies (2020-2023)
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[PMID: 3068032] PubMed record related to this compound for laboratory literature review
We found that a high level of Glu (875.42 g/g FW) was accumulated in the pad2-1 mutant compared to WT (494.96 g/g FW) while the GSH content in pad2-1 (4.91 g/g FW) was severely decreased to 5.9% of WT (82.94 g/g FW) (Fig