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They can affect cellular signaling pathways that produce antioxidant enzymes like SOD and catalase, which remove free radicals and minimize oxidative stress (183)

Can I drink alcohol on the same day I take my GLP-1 shot

The STEP-HFpEF and STEP-HFpEF DM trials investigated the efficacy of semaglutide (at a dose of 2.4 mg weekly) in patients with obesity-related HFpEF, with and without type 2 diabetes, respectively 28,29

This is probably most applicable in individuals with poor glutathione recycling and underlying oxidative stress