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When thyroid hormone levels drop, metabolic rate slows, often leading to unintended weight gain or difficulty losing weight despite dietary efforts
Rothberg, A
Are GLP-1 Medications Alone Enough to Help You
doi:10.2337/dc13-2759
At the proteolytic level, GLP-1 RAs may reduce muscle protease activity and modulate inflammatory pathways, thereby attenuating protein breakdown and contributing to muscle mass preservation [39, 84]
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