The relentless, rolling waves of nausea that hit during dose escalation drive roughly 10-17% of users to abandon treatment entirely, according to data from the STEP clinical trials
These aggregates are not only ineffective but can potentially trigger immune reactions at the injection site
the serendipitous discovery of exenatide by scientists fascinated with venom ( [22] ) ( [23] )), clinicians (adapting practice guidelines to incorporate these new therapies), patients (experiencing improved quality of life and weight loss), and public health experts (weighing the societal impact of widespread GLP-1 use)
Participants eating large meals had 41% nausea rates versus 22% for small meals
However, long-term effectiveness has not been demonstrated
A double-blind multicenter comparison of domperidone and metoclopramide in the treatment of diabetic patients with symptoms of gastroparesis