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GLUD1 has two co-enzyme binding sites: one in the NAD-BD that is able to bind ether NAD+ or NADP + and is directly involved in the catalytic process, and a second one, that has regulatory function, lying directly under the pivot helix, that can bind ADP, NAD + , or NADH, but does not bind NADPH well
doi: 10.1002/med.21662 16
Clinical Update 7/22/2022 Electrolytes for Hangovers
Determining your personal response requires trial, ideally with some attempt at blinding to reduce bias
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