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As such, the model was used to simulate how long it would take pharmacologically and toxicologically relevant concentrations of doxorubicin to yield a 70% reduction in GSH concentration, indicative of impaired cellular antioxidant defence, protein binding and cell death 19
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Genotype, enzyme activity, glutathione level and clinical phenotype in patients with glutathione synthetase deficiency
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- Glucan receptors Pattern recognition receptors (PRRs) are the typical cell surface receptor possessed by immune cells, including macrophages and dendritic cells that recognize PAMPs and other naturally occurring ligands, such as - glucans (156)
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