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Glutathione is also a cornerstone of the detoxification process

One possible side effect of drinking alcohol during Accutane treatment is liver damage

ROS enhances inflammation by activating MAPK, which subsequently phosphorylates downstream proteins to upregulate the expression of pro-inflammatory genes such as IL-6, TNF-, and IL-1 [90]

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Fyfe C, Grossman TH, Kerstein K, Sutcliffe J