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During autooxidation of glucose, enzymatic pathways, such as the NOX pathway, become the main sources of ROS 38,39
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The study further revealed that the combination of AOD9604 and hyaluronic acid injections surpassed the effectiveness of either hyaluronic acid or AOD9604 alone [9]
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7 patients with migraine episodes and vasomotor headaches, chronic tinnitus and psychogenic pain attacks were studied, and after intravenous administration on 5 consecutive days followed by 5 injections every 48-72 h, DSIP lowered the pain levels of 6 out of 7 patients significantly
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