RT-PCR Total RNA from cultured rat cortical cells was prepared using an ISOSPIN Cell & Tissue RNA kit (Nippongene, Tokyo, Japan)
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For Indian skin (Fitzpatrick IVVI) Alpha-arbutin has been shown in research to support melanin reduction across diverse skin types and may be particularly relevant for Fitzpatrick IV-VI individuals in Kerala where high UV exposure and genetic predisposition contribute to melasma and PIH
PubMed laboratory research record [PMID: 5001773] PubMed record related to this compound for laboratory literature review
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No invasive techniques are used, and no anesthesia is required