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DIO mice received 1, 5, 10 or 25 g per l per mouse of mGIPR-Ab/P3 or 25 g per l per mouse of IgG1 control injected ICV every 4 days for five treatments, with body weight and food intake monitored for 44 days
If the peptide is administered once in a way that creates a short signaling event, that protocol is functionally different from the same total amount divided across separate administrations
The interest in exploring this potential connection stems from emerging research into the anti-inflammatory properties of GLP-1 signaling and observations in patients with coexisting metabolic and inflammatory conditions
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