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Compared to hGH, AOD9604 offered similar adipose tissue effects without significantly increasing systemic growth factors, such as IGF-1
However, their clinical application requires rigorous evaluation of therapeutic efficacy, comprehensive safety profiling, and well-defined patient selection criteria
Mechanistic plausibility alone does not establish clinical benefit
BPC-157 has been researched for supporting gut health issues (inflammatory bowel conditions, leaky gut), tendon and ligament injuries, muscle tears, joint issues, post-surgical recovery, wound healing, and chronic inflammation
While RCTs remain the gold standard for intervention assessment, observational studies provide complementary evidence, especially when using objective biomarkers such as serum Vitamin B12, MMA, and homocysteine