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Shorey S, et al

Experimental Interaction and Research Focus Interaction with intracellular signalling networks in controlled laboratory models Influence on transcriptional behaviour and gene expression pathways Modulation of enzymatic sensitivity and biochemical response mechanisms Impact on mitochondrial activity and cellular energy regulation Support of repeat-exposure and comparative pathway validation studies Laboratory Research Applications Cellular Repair and Regeneration Research: Examining cellular response behaviour and regenerative pathway modelling in vitro

In mice treated with amoxicillin or ciprofloxacin, depletion of Lactobacillus reuteri (Firmicutes) led to reduced brain and serum GABA, downregulation of GABA-A receptors, and diminished 5-HT and DA, neurochemical changes that coincided with anxiety- and depression-like behaviors (Bibi et al., 2025)

Conclusion Axonal and neuronal necrosis, demyelination, and cyst formation were counteracted

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