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Recent Findings Preliminary data suggest that GLP-1 RA can modulate crucial pathways in the pathogenesis of IBD, such as chronic inflammation circuits, intestinal tight junctions, and gut microbiome dysbiosis, setting the stage for human trials to investigate the role of these agents in the treatment of IBD among people with or without diabetes and obesity

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Early 2023 ASA guidance favored holding daily agents on the day of surgery and weekly agents for one week, but 2024 multi-society guidance now recommends that most patients continue therapy before elective procedures

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A mild model may see very little benefit

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