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Generation of HNO and HSNO from nitrite by heme-iron-catalyzed metabolism with H(2)S
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2023 Sep 28;389(13):1221-1230
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The differential equations for the variables listed in Table1 are: Absorption and dosing APAP is absorbed from the gut into the portal circulation which flows into the liver
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N.Eckel-PassowJ
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GSSG is a product of the oxidation of GSH, which has no biological activity and needs to be reduced to GSH by consuming energy under the action of enzymes in order to resume its function
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This creates a metabolic bottleneck that slows everything down
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