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CP2, through partial inhibition of complex I, enhances mitochondrial energy efficiency, potentially increasing ATP levels in the brain

The effects of L-carnitine supplementation on lipid profiles in adults: a systematic review and dose-response meta-analysis

Pre-treatment of rats with 120 g/kg DSIP 20 minutes prior to subjection to hypoxia completely inhibited these hypoxia-induced reductions in mitochondrial respiratory activity

Clinically, observational studies have linked specific microbiome unit reduced microbial diversity, depletion of butyrate-producing taxa, and an altered estrobolome to higher breast cancer risk or more aggressive phenotypes, and small interventional trials and pilot studies have explored probiotic supplementation (commonly Lactobacillus and Bifidobacterium strains) (176), showing encouraging signals such as improvement in systemic inflammatory markers, attenuation of gastrointestinal and mucosal toxicities during chemotherapy, mitigation of antibiotic-associated diarrhoea, modest improvements in metabolic parameters and bone health, and favourable changes in gut microbial composition