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Any use outside approved indications would be considered off-label prescribing, which requires careful clinical justification and informed patient consent

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Nat Rev Endocrinol 8:728742 Rosenstock J, Raccah D, Koranyi L et al (2013) Efficacy and safety of lixisenatide once daily versus exenatide twice daily in type 2 diabetes inadequately controlled on metformin: a 24-week, randomized, open-label, active-controlled study (GetGoal-X)