The optimal amount depends on your typical dose range
Reduced expression of receptor subunits, imbalances in their levels, decreased glutamatergic and GABAergic neurotransmission, and altered energy metabolism are known to play a critical role in the progression of depression (64, 65)
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GI intolerance with GLP-1 RA use is a big deal
Unfortunately, factors like stress, illness, aging and toxin exposure can deplete our glutathione reserves
GLP-1s have a plethora of benefits ranging from reducing inflammation, to stimulating the immune system, to reducing oxidative stress, to boosting mitochondrial function, that lead to documented neurocognitive and cardiovascular protection