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This sustained-release pattern from weekly injections allows smaller total doses to produce comparable or stronger therapeutic effects than daily oral tablets, which is why injections often outperform oral formulations in clinical trials measuring weight loss and glucose control

The combination of GLP-1 and GIP receptor activation in the central nervous system may achieve more balanced and sustained effects on energy homeostasis compared to targeting either pathway alone

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While some of the animals had been given Mesna, others were administered with P