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Support the barrier

Keloid Senescent Fibroblast Elimination & SASP Suppression (Communications Biology, 2025) FOXO4-DRI Induces p53-pS15 Nuclear Exclusion and Apoptosis in Keloid Fibroblast Models A study published in Communications Biology (Nature Publishing Group, 2025) used single-cell RNA sequencing to characterise the senescent cell landscape in keloids pathological scars with tumour-like aggressiveness

Clinical Results

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Some of it is incomplete

Thus, ABCG2 may play a role not only in mediating HSC/HSPC self-renewal and differentiation, but also in promoting their survival against cytotoxic insult