NRF2/glutathione-mediated antioxidant defense pathway influences cisplatin resistance Another factor that could explain the different sensitivity between A549 and NCI H23 cell lines is an increased cisplatin detoxification, which can reduce cisplatin DNA damage, and as consequence, lower drug cytotoxicity
GGT (gamma-glutamyltransferase): Diagnostic Significance and Clinical Insights Authors: Payal Bhandari M.D., Amer Dankovi, Madison Granados Contributors: Hailey Chin, Vivi Chador, Nigella Umali Ruguian Key Insights The liver, known as the bodys chemical factory, processes proteins, fats, and cholesterol, supports energy production, detoxification, hormone regulation, and blood clotting
Moreover, although Ang-1 and Ang-2 are not known drugs for protecting the glycocalyx, intervening in Ang-1 and Ang-2 may serve as targets for inhibiting glycocalyx degradation
The global and regional burden of stroke
The very same pathways that make it a regenerative jack-of-all-trades could also pose dangers especially regarding cancer and unregulated cell growth
Mahboob M, Rahman MF, Grover P