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Overlapping binding sites of GLP-1 and Fab 3F52 The -helix of the GLP-1R ECD is a critical part of the GLP-1 binding site as shown previously by x-ray crystallography and it is also the primary binding site of Fab 3F52 as shown in this study 31

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Cell 150 , 1227 (2012)

This can be convenient for patients on higher maintenance doses because each injection requires less liquid

b Novo Nordisk defines access as covered when brand is available on formulary with or without restrictions

Constipation and abdominal pain were also less common with Zepbound , suggesting that it may be more comfortable for some users