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Pharmacological inhibition of ferroptosis alleviates fibrotic changes in TGF--treated HK-2 cells In the present study, TGF- was identified as an inducer of fibrotic changes and effectively stimulated fibrosis in the HK-2 cells, paralleling the fibrotic processes observed in the UUO mouse model in vivo [24]
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Vestgaard M, Nielsen LR, Rasmussen AK, Damm P, Mathiesen ER
This combination is supplied as a blended lyophilized peptide formulation designed for precise laboratory handling and is suitable for in-vitro and preclinical research models
To support the role of immunemediated inflammation, we also evaluated TNF levels, the master regulator of the immune response, as the major contributor during the development and progression of heart failure
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