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Constipation is a recognized gastrointestinal side effect in major GLP-1 weight-loss trials, especially during dose escalation or when reduced appetite leads people to eat and drink less

In addition, a further increase in NtGSTU1 expression at 3 and 6 h after virus inoculation was associated with enhanced HR-type resistance (i.e., significantly less necrotic lesions and reduced TMV-replication) in plants with a sufficient sulfate supply (Kirly et al., 2012)

The market for booster shots has dramatically declined, and Pfizer had to take doses of its pill back from the government last year because of low demand