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A 12-week study in humans where participants were given 500mg of berberine 3 times a day resulted in: an average weight loss of 5lb (2.3kg) a 23% reduction in triglycerides (a type of blood fat) a 12.2% reduction in cholesterol However, animal studies show that berberine has a very low bioavailability of less than 1% (how much of it is absorbed in your bloodstream), which may affect its effectiveness

Consult your healthcare provider before making medical decisions, especially if a reaction is new, worsening, recurrent, or concerning

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Ishikawa R, Saito K, Misawa T, Demizu Y, Saito Y

To date, numerous drugs containing antioxidant-like substances have been investigated to either support or replace standard treatments for vitiligo (Table 1)