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While patients in the placebo arm had lost an average of 0.880.08% of their baseline body weight by 104 weeks post-randomization, patients in the semaglutide arm had lost an average of 9.390.09%

Critically, this redox adaptation is a key mechanism of resistance to radiotherapy and many chemotherapeutic agents, such as cisplatin and doxorubicin, which depend on generating oxidative damage to exert their cytotoxic effects [33]

doi: 10.1620/tjem.221.287 64 Seron-FerreMValenzuelaGJTorres-FarfanC

Some patients report mild fatigue, which may relate to reduced caloric intake, adjustment to the medication, or changes in eating patterns

Rather than go without therapy, our sublingual is a good alternative, although not quite as strong as the injectable