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The cells were treated with rotenone (0.055 M) for 24 or 48 h and the metabolic activity measured by the Alamar Blue assay (Fig

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Semaglutide was originally approved by the Food and Drug Administration (FDA) to treat type 2 diabetes by lowering glucose levels in the body

These glucagon-based chimeric peptides were generated by amino acid substitutions to the glucagon sequence aimed at increasing potency at the GLP-1R and conferring balanced co-agonism at both receptors

& Maier, C

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