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For serum metabolic analysis, 50 l serum samples was used and extraction procedure similar to bone samples was applied by adding ribitol as internal standard followed by procedures as stated before ( 2.8 Bone mechanical testing 2.8.1 Three-point bending Femur bones were kept in saline-soaked gauze before the testing and 3-point bending test was performed as described before ( 2.8.2 Nanoindentation The femur was cut from mid-diaphysis with a low-speed diamond blade saw (IsoMet

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Compared with regular L-Carnitine, the acetylated structure provides better stability and bioavailability for consistent formulation performance