In conclusion, REB exerts protective effects against LPS-induced ALI through modulation of inflammatory and oxidative stress pathways involving the PDE4B/cAMP/PKA/p-CREB axis and NF-B signaling
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Affiliation: 1 College of Medicine, University of Florida, Gainesville, FL 32608, USA Email: [email protected] ORCID: Affiliation: 1 College of Medicine, University of Florida, Gainesville, FL 32608, USA ORCID: Affiliation: 1 College of Medicine, University of Florida, Gainesville, FL 32608, USA ORCID: Affiliation: 1 College of Medicine, University of Florida, Gainesville, FL 32608, USA ORCID: Affiliation: 1 College of Medicine, University of Florida, Gainesville, FL 32608, USA ORCID: Affiliation: 1 College of Medicine, University of Florida, Gainesville, FL 32608, USA ORCID: Affiliation: 1 College of Medicine, University of Florida, Gainesville, FL 32608, USA ORCID: Affiliation: 2 Department of Neurosurgery, University of Florida, Gainesville, FL 32608, USA ORCID: Explor Drug Sci
The peptide is establishing tissue saturation