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The body interprets rapid fat loss as a significant stressor, releasing inflammatory mediators as part of the adaptive response

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During this metabolic transition, muscle fibers may experience mild inflammation or soreness, similar to the feeling after intense exerciseeven though no physical exertion occurred

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Furthermore, -KG, which is produced from pyruvate in the TCA cycle, is known for its ability to bind to and remove ROS, a contributor to oxidative stress 24

Whole foods like lean proteins, vegetables, and complex carbohydrates deliver sustained energy and nutrients, while processed foods high in sugar or fat may trigger nausea or GI upset when combined with GLP-1 medication