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Key points A combination of spirochaetal and host genetic factors shape the outcome of Lyme arthritis, which ranges from mild, antibiotic-responsive joint inflammation to persistent, antibiotic-refractory autoinflammatory or autoimmune synovitis

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In 2024, a multi-society clinical practice guideline was issued jointly by the American Gastroenterological Association, the American Society for Metabolic and Bariatric Surgery, the American Society of Anesthesiologists (ASA), the International Society of Perioperative Care of Patients with Obesity, and the Society of American Gastrointestinal and Endoscopic Surgeons [112]