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In the same 2025 study by Qeadan and colleagues, individuals with a history of opioid use disorder (n=503,747) prescribed GLP-1 medications had about a 40% lower rate of opioid overdose events during the 2-year follow-up period (Qeadan et al., 2025)

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Kumar said, "It's all over social media

Ask whether a slower dose escalation or a lower maintenance dose might reduce sexual side effects while preserving weight loss benefits

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Aim for 25 to 35 grams of fiber daily, but increase gradually