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This means increasing the dose more slowly than usual

Geissenberger F, Schwarz F, Probst M, Haberl S, Parkhe A, Faul C, Von Lewinski D, Kroencke T, Schwaiblmair M, Von Scheidt W, Berghaus TM (2020) Obstructive sleep apnea is associated with pulmonary artery thrombus load, disease severity, and survival in acute pulmonary embolism

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These antibiotics have been known to cause fluctuations in blood sugar levels