TB4 (Thymosin Beta-4) is a naturally occurring peptide found throughout the body that regulates actin dynamics, recruits stem cells and progenitor cells to injury sites, reduces inflammation, and drives new blood vessel formation
doi.org/10.1002/oby.70100 5Healthline (May 11, 2026)
It is also used for diabetic patients who already have cardiovascular disease, to help lower the risk of major cardiovascular events such as heart attack or stroke
Perinatal mortality in Type 2 diabetes mellitus
Given these benefits, it is imperative that we continue exploring their broader therapeutic potential beyond glucose lowering. At the studys conclusion, Wu and his team found that study participants taking GLP-1 agonists had a significantly lower cumulative risk of developing dementia namely, 10% with an incidence of about 2.5%
This pattern suggests maximal receptor occupancy at the intermediate dose