they may also have direct effects in the brain (animal studies show neuroprotection and reduced amyloid/tau pathology)
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While the study establishes a compelling systemic role for SLC25A45 in fuel switching, important questions remain regarding the tissue-specific contributions of this pathway and how carnitine biosynthesis and utilization are differentially regulated across dietary, disease, and sexually dimorphic contexts
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Prev Nutr Food Sci
[11] [12] The combination might theoretically offer complementary cardiovascular support, but robust evidence is lacking, and neither is included in UK clinical guidelines for cardiovascular disease management or lipid modification