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"Overall, the field is moving toward treatments that meaningfully improve weight, blood sugar, and cardiovascular risk at the same time," Dr

Stable medication protocols are generally preferred during periods of hormonal transition

In STEP 1, a 68-week trial, adults on branded semaglutide 2.4 mg (Wegovy) plus diet and exercise lost roughly 15% of their body weight on average

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This natural fluctuation reflects shifts in water retention, metabolism, hormonal cycles, and digestive timing rather than signaling treatment failure

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