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N-acetylcysteine administration Intravenous N-acetylcysteine is the antidote to treat paracetamol overdose and is virtually 100% effective in preventing liver damage when given within 8 hours of the overdose

doi: 10.1093/gerona/glad022 90 ArvatEdi VitoLMaccagnoBBroglioFBoghenMFDeghenghiRet al

(PubMed) Naghashpour M, Majdinasab N, Shakerinejad G, et al

Those on around 300 mg had an 83 percent greater risk of dying, and those on 400 mg or more appeared to double their risk for death