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The medication's appetite-suppressing effects fade, and you may notice increased hunger and food cravings returning to pre-treatment levels or potentially higher

"Everything with hormones is many layers deep for the cause, but the biggest factors for PCOS come from high DHEA (a building block used to make other hormones), which leads to symptoms of elevated androgens like testosterone

Martin Whyte, an associate professor of metabolic medicine at the University of Surrey, explains one possible theory as to why people tend to regain weight after they stop these medications

2 Mechanisms of redox regulation in the CNS 2.1 GSH as an antioxidant in the brain The brain, being one of the most metabolically active organs in the body, requires a large share of oxygen relative to its mass