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Doses above 2ml per injection show no additional benefit in controlled trials and increase injection site discomfort without improving methylation efficiency
Higher body mass index was associated with greater MI risk reduction (: -0.09, p = 0.03) in GLP-1RA users
When functioning properly, GLP-1 makes it easier to eat less and feel full on smaller portions
This single dose increase from 5mg triggered a catastrophic 27-point HRV collapse, more impact than all previous escalations combined
A subsequent Danish cohort study of 424,152 patients with type 2 diabetes found roughly a doubling of five-year NAION risk a smaller effect, but in the same direction
GLP-1 Diabetes and Weight Loss Drug Side Effects: Ozempic Face and More
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