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Temporal trends and factors associated with diabetes mellitus among patients hospitalized with heart failure: findings from Get with the GuidelinesHeart Failure registry
Cardiovascular risk increases with a higher LDL particle count
Gene expression analysis showed upregulation of survival pathways (Egr1, Akt1, Kras, Src, Foxo, Srf, VEGFR2, NOS1, NOS3) and downregulation of inflammatory mediators (NOS2, NFB)
Liu, Q., Kriksunov, I
Furthermore, PBMCs derived from G6PD-d donors and G6PD-knockdown human monocytes displayed reduced signaling through the NLRP3 inflammasome, p38 MAPK and c-Fos caused by decreased modulatory NADPH-dependent ROS
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