Oral vs injectable GLP-1: does delivery method change the timeline The GLP-1 space is expanding beyond weekly injections
By week sixteen, 89% of participants on 8 mg and 93% on 12 mg had achieved normal liver fat levels below 5%
There are different drugs within the GLP-1 category, but semaglutide, which is a weekly injectable medication, is among the best known due to its large impact on weight and the fact that it was the first GLP-1 approved for weight loss
For optimal results, complement tirzepatide with a healthy diet, regular exercise, sufficient sleep, and constant provider check-ins
Semaglutide enhances and prolongs these effects, leading to several key benefits: Appetite Regulation and Satiety: Semaglutide acts on the brains appetite centers, reducing hunger signals and increasing feelings of fullness
Moreover, a retrospective real-world study shows that both GLP1-RA and SGLT-2 inhibitors reduce the 10-year risk for cardiovascular disease in patients with T2D in primary cardiovascular prevention [17], although SGLT-2 inhibitors seem to have a greater cardioprotective benefit compared to GLP-1RA when used for secondary prevention among adults with T2D [18]