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Continuous GH elevation (as with exogenous GH administration) suppresses this natural pulsatility and can downregulate GH receptors
This is not a formal ceiling because no FDA-approved limit exists, but it represents the upper range of what is supported by preclinical scaling and provider experience
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[ 13 ] Cortisol, often referred to as the body's primary stress hormone, normally follows an opposite pattern to melatonin, rising in the morning and declining throughout the day
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