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2) In addition to testing various doses of cagrilintide, the peptide was also tested in combination with semaglutide, a GLP-1 receptor agonist, in order to assess the impact treatment has on HbA1c levels in participants diagnosed with type 2 diabetes mellitus

This will provide insights into the development of more potent and selective inhibitors

9 BombaM.GranzottoA.CastelliV.MassettiN.SilvestriE.CanzonieroL.et al (2018)

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Some individuals find that they need to titrate up to the maximum dose of a given GLP-1 drug fairly quickly, while others are able to make progress on a lower dose for an extended period