Funding This work was supported by grants from the National Natural Science Foundation (81972259, 82273394), the Clinical Trials Fund from Nanjing Drum Tower Hospital and the Affiliated Hospital of Nanjing University Medical School (2024-LCYJ-PY-01), Suzhou Municipal Health Commission (SKYD2022034), and the discipline construction and support project (XKTJ-JD202006) of the Second Affiliated Hospital of Soochow University
Delivered as an injection, Wegovy (Novo Nordisk) is best known as a weight-loss medication
Users who became relaxed about nutrition during the protocol may need to tighten up to preserve their results
Once inactivated by DPP-4, GLP-1 is removed from the body through the actions of the kidneys (Figure 3)
NICE guidelines recommend evidence-based weight management through dietary modification (600 kcal/day deficit), 150300 minutes weekly moderate-intensity physical activity, and behavioural change strategies
What makes Ipamorelin particularly valuable for research is its selectivity