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Further the interactions of the non-covalently bound coenzyme ThDP-magnesium with the protein component are at five critical sites containing arginines (Arg 101, Arg 318, Arg 395, Arg 401 and Arg 474and Asp155) [101] contribute to dimer formation, stability or catalytic activity [102, 96]

4A) [77]

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The DNA regulatory sequence accountable for stimulation by indirect antioxidant pathway inducers was identified as an antioxidant response element (ARE), while Nrf2 was subsequently recognized as the xenobiotic-activated receptor (XAR) major regulator responsible for the activation of ARE-dependent drug metabolizing enzymes [39]

Braz J Pharm Sci

Supernatants were quantified and analysed by western blotting