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79 This upregulation correlates with obesity severity, adipocyte hypertrophy, and adverse glucometabolic status, reflecting a tightly regulated interplay between autophagy, tissue remodeling, and metabolic stress

164 The NAD + /SIRT1 signaling pathway functions as a central node linking nutrient sensing, autophagy regulation, and ER adaptation

Additionally, participants consumed approximately 23 times the recommended daily intake over a period of 10 years

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