At the molecular level, region-, sex-, and age-specific changes in gene expression were observed, particularly the upregulation of Mc4r
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Specifically, we applied genetic proxies for l-carnitine to genome-wide association studies (GWAS) of CVD and its risk factors (type 2 diabetes, glucose, HbA1c, insulin, low-density lipoprotein (LDL)-cholesterol, high-density lipoprotein (HDL)-cholesterol, triglycerides, apolipoprotein B, and blood pressure)